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Registros recuperados: 193 | |
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Gabriel Leitner; Ana-Maria Anug; Uzi Merin; Nissim Silanikove. |
*Background*
Repeated research findings over the last 4 decades show that involution of mammary glands in dairy cows did not regress to same extend as that noticed in other mammalian species.

*Methodology/Principal Findings*
We took an advantage of a rare event in the normal modern dairy farming: A cow that was false-positively identified as being pregnant was "dried up" (i.e., induced into involution) conventionally about 60 before her expected parturition. This cow was culled, and samples of her mammary gland tissue were examined for gross histology. In this study we demonstrate for the first time that modern dairy cow may undergo extensive obliteration of the... |
Tipo: Manuscript |
Palavras-chave: Cancer; Developmental Biology; Immunology. |
Ano: 2007 |
URL: http://precedings.nature.com/documents/846/version/2 |
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John R. Skoyles. |
1.	After weaning, human hunter-gatherer juveniles receive substantial (≈3.5-7 MJ day^-1^), extended (≈15 years) and reliable (kin and nonkin food pooling) energy provision.
2.	The childhood (pediatric) and the adult human brain takes a very high share of both basal metabolic rate (BMR) (child: 50-70%; adult: ≈20%) and total energy expenditure (TEE) (child: 30-50%; adult: ≈10%).
3.	The pediatric brain for an extended period (≈4-9 years-of-age) consumes roughly 50% more energy than the adult one, and after this, continues during adolescence, at a high but declining rate. Within the brain, childhood cerebral gray matter has an even higher 1.9 to... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Neuroscience; Evolutionary Biology. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/1856/version/2 |
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Tiefeng You; I. C. Baianu. |
The soybean-derived products are among the most important agricultural products in the USA and the world. Conventional analytical methods for soybean composition analysis are both time consuming and costly. Faster and less expensive methods are required for most practical applications. To improve the accuracy, reliability and sensitivity of NIR, major advancements in instrumentation, as well as, data analysis / calibration methodology are required. Novel NIR instruments, such as DA-NIR and FT-NIR spectrometers developed in recent years have the potential for improving significantly the quantification of soybean composition at a reasonable cost. We present representative calibrations and data for intact soybean composition analysis obtained at the... |
Tipo: Manuscript |
Palavras-chave: Biotechnology; Chemistry; Developmental Biology; Genetics & Genomics; Molecular Cell Biology; Bioinformatics; Plant Biology. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6253/version/1 |
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Michael E. Baker; Charlie Chandsawangbhuwana. |
*Background.* The origins of steroid-dependent regulation of the vertebrate estrogen receptor (ER) are poorly understood. Genes with statistically significant sequence similarity to vertebrate ERs have been found in lamprey, a basal vertebrate, and amphioxus, a basal chordate. Motif analysis of these sequences provides an opportunity to investigate early events in the evolution of the ER.
*Results.* We used artificial intelligence-based software to construct twelve motifs specific to the estrogen-binding domain of ER[alpha] and ER[beta] in land vertebrates and teleosts. We mapped these ER-specific motifs onto the sequences of lamprey, amphioxus, invertebrate and selected vertebrate ERs and amphioxus, Ciona and human estrogen-related... |
Tipo: Manuscript |
Palavras-chave: Cancer; Developmental Biology; Ecology; Evolutionary Biology. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/1542/version/2 |
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Tracy Alloway; Ross Alloway. |
Multiple demands comprise the efficiency of attentional control. There is abundant evidence that when an individual attempts two or more attentionally demanding activities at the same time, the allocation of attention to the tasks is limited and performance suffers as a result. Yet, recent technological innovations require many individuals to manage multiple digital technologies simultaneously or to switch attentional control between tasks. The ability to multitask with various digital technologies involves dividing attention, switching between tasks, and keeping track of multiple strands of information in working memory. |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Neuroscience. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/5603/version/1 |
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Jeni Chandar Padua; Basil Rose MR. |
Radiation exposure during gestation causes mutation in the fetus leading to birth defects in the newborn. On a survey of the coastal villages of Kanyakumari District, Tamilnadu, India, high levels of background radiation were detected, which was suggestive of inducing mutations, and congenital abnormalities in the exposed population. To substantiate the dangerous impact of such natural radioactive emissions, we have established an avian model of irradiation-induced birth defect in chicks hatched from eggs exposed to natural radioactive beach sand. The hatched experimental chicks exhibited severe locomotor disability and extreme malformations. Our study proves for the first time, that natural beach sand radiation induces severe developmental abnormalities.... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Earth & Environment. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6191/version/1 |
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Victor H. Han; Gilles Lajoie; Jennifer Ballard; Aaron Booy; Nicholas Carruthers; Delfina Siroen. |
Preeclampsia is a pregnancy-associated disorder that manifests as a sudden increase in maternal blood pressure accompanied by proteinuria. Because the placenta is a key organ in preeclampsia, we used proteomic and lipidomic analyses to compare placentae from preeclamptic and gestational age matched control pregnancies. Fatty acid binding protein 4 (FABP4), enoyl-CoA dehydrogenase and delta-3,5-delta-2,4-dienoyl-CoA isomerase had altered abundance in preeclamptic placentae compared to controls. FABP4 placental protein and RNA and plasma levels were all increased in early-onset preeclampsia (prior to 28 weeks gestation) compared to controls (6-fold, 3.3-fold and 3.5-fold respectively). After 28 weeks, FABP4 protein in control placenta and plasma increased to... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Genetics & Genomics. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/4885/version/1 |
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Yaroslav Strokovskyy. |
We propose a hypothetic mechanism of ordering and shaping cells during _C. elegans_ embryogenesis. The mechanism is based on the assumption that during each round of division of cells, daughter cells acquire electric charges from its mother cells (charge conservation law is taken into account). Between the acts of division, the total electric field, generated by a system of charged cells, change relative positions of the charged cells within the region. In one’s turn, the positions of the charged cells determine the pattern of the electrostatic field. A mathematical model of such self-consistent mechanism is developed. The process of developing the sixteen-cell structure starting with one cell is simulated. The results correspond to the known... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/4277/version/1 |
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Robert Hauser; Alberto Palloni. |
Numerous studies find a positive relationship between cognitive ability, IQ as measured in childhood or youth, and subsequent survival. Explanations range from the idea that low ability is an indicator of adverse systemic events in early life to the idea that high cognitive functioning is required continuously to maintain health and reduce threats to survival. The Wisconsin Longitudinal Study (WLS) has followed a large cohort of Wisconsin high school seniors from ages 18 to 69. As expected, in the WLS survival varies positively with adolescent IQ. However, rank in high school class accounts completely for the relationship between IQ and survival, and it has a much larger effect on survival. These findings suggest that cognitive functioning improves... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology. |
Ano: 2010 |
URL: http://precedings.nature.com/documents/4340/version/1 |
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N V K V Prasad Tollamadugu; S R Venkata Kambala; Benjamin Convery; Ravi Naidu. |
Nanoparticles are considered to be the building blocks of nanotechnology. Biosynthesis of nanoparticles using plant material is an exciting and relatively new developing research area in nanobiotechnology. In the present study, Eucalyptus leaves were collected from Olive pink botanical garden, Alice Springs, Australia and were used to synthesize silver nanoparticles. Cubical structured and well monodispersed silver nanoparticles were formed with an average size of 50nm. The formed silver nanoparticles are found to have promising applications in medicine as good antimicrobial agents. To the best of our knowledge this is the first report on exploiting indigeneous Australian plant sources for the synthesis of metallic nanoparticles. |
Tipo: Poster |
Palavras-chave: Developmental Biology. |
Ano: 2011 |
URL: http://precedings.nature.com/documents/6307/version/1 |
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Rodrick Wallace. |
We extend a cognitive paradigm for gene expression to the epigenetic epidemiology of mental disorders, recognizing the fundamental role that culture plays in human biology as another heritage mechanism parallel to, and interacting with, the more familiar genetic and epigenetic systems. In the mathematical model, culture acts as another tunable epigenetic catalyst that both directs developmental trajectories and becomes convoluted with individual ontology via a mutually interacting crosstalk mediated by a social interaction that is itself culturally driven. We call for the incorporation of embedding culture as an essential component of the epigenetic regulation of human mental development and its dysfunctions, bringing what is perhaps the central reality of... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Genetics & Genomics; Neuroscience. |
Ano: 2009 |
URL: http://precedings.nature.com/documents/3894/version/1 |
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Leonardo Varuzza; Arthur Gruber; Carlos A. B. Pereira. |
Most of the statistical tests currently used to detect differentially expressed genes are based on asymptotic results, and perform poorly for low expression tags. Another problem is the common use of a single canonical cutoff for the significance level (p-value) of all the tags, without taking into consideration the type II error and the highly variable character of the sample size of the tags.

 This work reports the development of two significance tests for the comparison of digital expression profiles, based on frequentist and Bayesian points of view, respectively. Both tests are exact, and do not use any asymptotic considerations, thus producing more correct results for low frequency tags than the chi-square test. The... |
Tipo: Manuscript |
Palavras-chave: Developmental Biology; Bioinformatics. |
Ano: 2008 |
URL: http://precedings.nature.com/documents/2002/version/2 |
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Registros recuperados: 193 | |
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